Urine podocin:nephrin mRNA ratio (PNR) as a podocyte stress biomarker

Adiponectin/Leptin ratio as a Biomarker of Acute Metabolic Stress

Alteration of podocyte phenotype in the urine of women with preeclampsia

Podocyte injury has been suggested to induce phenotypic alteration of glomerular podocytes and accelerate the detachment of podocytes from the glomeruli resulting in podocyturia. However, it is not clear whether podocyte phenotypic alteration occurs in the urine of women with preeclampsia (PE). Seventy-seven and 116 pelleted urine samples from 38 and 18 women at various stages of normal and PE ...

A Pilot Study of CK19, CK20 and GCC mRNA in the Peripheral Blood as a Colorectal Cancer Biomarker Panel

Colorectal cancer remains one of the major cancer- related deaths despite progress in the treatment during past decades. Detection of disease at earlier stages reduces its mortality. The aim of current study was to investigate expression of Cytokeratin 19 (CK19), Cytokeratin 20 (CK20) and Guanylyl Cyclase C (GCC) mRNA in peripheral blood of non- metastatic colorectal cancer patients which may r...

Urine albumin as a biomarker in acute kidney injury.

ACUTE KIDNEY INJURY (AKI) is a common clinical condition that is associated with significantly high rates of morbidity and mortality particularly in critically ill patients (1, 2, 10, 18). Despite fundamental advances in understanding the etiology and pathophysiology of AKI the current therapeutic approaches remain limited to supportive measures (e.g., dialysis). Treatment for AKI is confounded...

Urine menthol as a biomarker of mentholated cigarette smoking.

OBJECTIVES Menthol cigarettes are smoked by 27% of U.S. smokers, and there are concerns that menthol might enhance toxicity of cigarette smoking by increasing systemic absorption of smoke toxins. We measured urine menthol concentrations in relation to biomarkers of exposure to nicotine and tobacco carcinogens. METHODS Concentrations of menthol glucuronide (using a novel analytical method), ni...